Hyperparathyroidism signs

Fatigue, drinking too much water, frequent urination, nocturia, bone and joint pain, constipation, loss of appetite, nausea, itchiness and depression are the most common symptoms.


Majority of patients have non-specific symptoms such as malaise, getting tired quickly !!!!  That means these symptoms can also be seen in very different diseases.


The rates of bone fracture and heart disease are higher among the patients with hyperparathyroidism.


Hyperparathyroidism may cause calculi (kidney stones). PTH and calcium tests should be studied in every patient who has kidney stone.


In delayed treatment cases, 30-50% of the bone density may be lost in !!!  Severe bone loss may occur.


Bone tumors may develop in ingnored patients (Brown tumor).  These tumors are not cancer.  However, they may cause bone fractures.


An elevated level of calcium together with a raised level of parathyroid hormone and low levels of phosphorus are typically found in hyperparathyroidism.


24 hours urine calcium is elevated.


Ultrasonography and sestamibi scintigraphy (MIBI) are usually used to determine the location of parathyroid lesions


   
The picture on the left; demonstration of the localization of the adenoma in a patient who previously undergone surgery and no adenoma could be detected, The picure on the right; localization of the adenoma in scintigraphy

 
Tumor development in the mandible (Brown tumor associated with hyperparathyroidism)